The definitive text and reference on pediatric radiation oncology is now in its thoroughly revised and updated Fourth Edition. This edition features a brand-new section on intensity modulated radiation therapy (IMRT), detailed information on three-dimensional treatment planning, and diagrams showing three-dimensional treatment plans for brain tumors, retinoblastoma, sarcomas, and neuroblastoma. The authors review the most recent clinical trials on management of leukemia, supratentorial and infratentorial brain tumors, retinoblastoma, neuroblastoma, Hodgkin´s disease, non-Hodgkin´s lymphoma, Ewing´s sarcoma, osteosarcoma, rhabdomyosarcoma, and Wilms´ tumor. This edition also includes new information on the late effects of cancer treatment and the risk of treatment-induced secondary malignant neoplasms.